Description
Aliases
Actin-related protein 2, Actin-like protein 2, ACTR2, ARP2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P61160
Immunogen
Recombinant human Actin-related protein 2 protein (1-160AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Literature
[1]Initial characterization of the human central proteome.”Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011). [2]Lysine acetylation targets protein complexes and co-regulates major cellular functions.”Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.Science 325:834-840(2009). [3]Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity.”Gournier H., Goley E.D., Niederstrasser H., Trinh T., Welch M.D.Mol. Cell 8:1041-1052(2001).Additional information
| Size | 50μl, 100μl |
|---|
