AK1 Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 39766 Categories: ,

Description

Aliases

AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase, Myokinase, AK1

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P00568

Immunogen

Recombinant human Adenylate kinase isoenzyme 1 protein (1-194AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Adenylate kinase isoenzyme 1

Literature

[1]”Red cell adenylate kinase deficiency: molecular study of 3 new mutations (118G>A, 190G>A, and GAC deletion) associated with hereditary nonspherocytic hemolytic anemia.” Corrons J.-L., Garcia E., Tusell J.J., Varughese K.I., West C., Beutler E. Blood 102:353-356(2003). [2]”Severe erythrocyte adenylate kinase deficiency due to homozygous A–>G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia.” Qualtieri A., Pedace V., Bisconte M.G., Bria M., Gulino B., Andreoli V., Brancati C. Br. J. Haematol. 99:770-776(1997). [3]”Crystal structure of human AK1A in complex with AP5A.” Structural genomics consortium (SGC) Submitted (MAR-2007).

Additional information

Size

50μg, 100μg

Certificate of Analysis