Antipain dihydrochloride
Price range: $115.76 through $393.58
Antipain dihydrochloride is a protease inhibitor, originally produced by actinomycetes.
| Size | 5 mg, 10 mg, 25 mg |
|---|
General Description
Antipain dihydrochloride is a protease inhibitor, originally produced by actinomycetes. It reversibly inhibit serine/cysteine proteases (cathepsin A, B, and D as well as papain) and some trypsin and trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration of antipain can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells. Antipain acts by forming a hemiacetal adduct between the aldehyde group of the inhibitor and the active serine of the proteinase. Effective at concentrations range from 1 to 100 μM.
Molecular Formula:Â Â Â C27H44N10O6.2HCl
Molecular weight:Â Â Â Â Â 677.62
CAS Number:Â Â Â Â Â Â Â Â Â 37682-72-7
Appearance:Â Â Â Â Â Â Â Â Â Â White to off-white solid
Solubility:Â Â Â Â Â Â Â Â Â Â Â Â Water (> 50 mg/ml) or DMSO (5 mg/ml)
Purity:               ≥97% by HPLC
Storage:              Store at -20 ℃. Protect from light and moisture
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