ARL4A Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 39970 Categories: ,

Description

Aliases

ARL4A, ARL4

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P40617

Immunogen

Recombinant human ADP-ribosylation factor-like protein 4A protein (2-200AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.” Hofmann I., Thompson A., Sanderson C.M., Munro S. Curr. Biol. 17:711-716(2006). [2]”ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin.” Bhamidipati A., Lewis S.A., Cowan N.J. J. Cell Biol. 149:1087-1096(1999). [3]”ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli.” Lin C.Y., Huang P.H., Liao W.L., Cheng H.J., Huang C.F., Kuo J.C., Patton W.A., Massenburg D., Moss J., Lee F.J. J. Biol. Chem. 275:37815-37823(1999).

Additional information

Size

50μg, 100μg

Certificate of Analysis