B3GNT5 Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 40131 Categories: ,

Description

Aliases

Lactosylceramide 1, 3-N-acetyl-beta-D-glucosaminyltransferase , Lactotriaosylceramide synthase, Lc(3)Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1, 3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1, 3-Gn-T5, Beta-1, 3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5, B3GNT5

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q9BYG0

Immunogen

Recombinant human Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein (65-344AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc4Cer; paragloboside), resulting in the synthesis of Lc3Cer and neolactopentaosylceramide (nLc5Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.”Henion T.R., Zhou D., Wolfer D.P., Jungalwala F.B., Hennet T.J. Biol. Chem. 276:30261-30269(2001). [2]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.Submitted (MAR-2005).

Additional information

Size

50μg, 100μg

Certificate of Analysis