Description
Aliases
Apoptosis regulator Bcl-W, BCLW, KIAA0271, BCL2L2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q92843
Immunogen
Recombinant human Bcl-2-like protein 2 protein (2-193AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]Initial characterization of the human central proteome. Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011). [2]System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011). [3]The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity. Hinds M.G., Lackmann M., Skea G.L., Harrison P.J., Huang D.C.S., Day C.L. EMBO J. 22:1497-1507(2003).Additional information
Size | 50μg, 100μg |
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