Bcr(Phospho-Tyr177) Antibody

$454.00

Cat. No.: 38798 Categories: ,

Description

Aliases

BCR; BCR protein; BCR1

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P11274
NCBI Protein: NP_004318.3

Immunogen

Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N) derived from Human Bcr.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Predicted MW: 210kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.Sattler M, et al. Mol Cell Biol. 1999 Nov; 19(11): 7473-7480.Li S et al. EMBO J. 2001 Dec 3; 20(23): 6793-6804.Million RP, et,al. Mol Cell Biol. 2004 Jun; 24(11): 4685-4695.Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Tyr177

Additional information

Size

100?l

Certificate of Analysis