Caveolin-2 Antibody

$425.25

Cat. No.: 11344 Categories: ,

Description

Aliases

CAV,

Antibody Type

Polyclonal Antibody

Uniprot ID

P51636

Immunogen

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

WB Recommended dilution: Predicted MW: 18 22kdWestern Blot: 1:500~1000

Background / Function

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.

Conjugate

Unconjugated

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Additional information

Size

100?l

Certificate of Analysis