CENPB Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 40011 Categories: ,

Description

Aliases

Major centromere autoantigen B, Centromere protein B, CENP-B, CENPB

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P07199

Immunogen

Recombinant human Major centromere autoantigen B protein (1-165AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”The MGC Project TeamGenome Res. 14:2121-2127(2004). [2]”Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells.”Orthaus S., Biskup C., Hoffmann B., Hoischen C., Ohndorf S., Benndorf K., Diekmann S.ChemBioChem 9:77-92(2008). [3]”Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.”Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. IIIJ. Proteome Res. 7:1346-1351(2008).

Additional information

Size

50μg, 100μg

Certificate of Analysis