CEP83 Antibody, Biotin conjugated

$231.52$415.64

SKU: 57633 Categories: ,

Description

Aliases

Cep83, Cep83, Renal carcinoma antigen NY-REN-58, CEP83, CCDC41

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q9Y592

Immunogen

Recombinant human Centrosomal protein of 83 kDa protein (1-568AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]Mutations of CEP83 cause infantile nephronophthisis and intellectual disability.Failler M., Gee H.Y., Krug P., Joo K., Halbritter J., Belkacem L., Filhol E., Porath J.D., Braun D.A., Schueler M., Frigo A., Alibeu O., Masson C., Brochard K., Hurault de Ligny B., Novo R., Pietrement C., Kayserili H. Saunier S.Am. J. Hum. Genet. 94:905-914(2014). [2]CCDC41 is required for ciliary vesicle docking to the mother centriole.Joo K., Kim C.G., Lee M.S., Moon H.Y., Lee S.H., Kim M.J., Kweon H.S., Park W.Y., Kim C.H., Gleeson J.G., Kim J.Proc. Natl. Acad. Sci. U.S.A. 110:5987-5992(2013) .

Additional information

Size

50μg, 100μg

Certificate of Analysis