EIF4EBP3 Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 41359 Categories: ,

Description

Aliases

4E-BP3, eIF4E-binding protein 3, EIF4EBP3

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O60516

Immunogen

Recombinant human Eukaryotic translation initiation factor 4E-binding protein 3 protein (1-100AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Team Genome Res. 14:2121-2127(2003). [2]”4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family.” Poulin F., Gingras A.-C., Olsen H., Chevalier S., Sonenberg N. J. Biol. Chem. 273:14002-14007(1997).

Additional information

Size

50μg, 100μg

Certificate of Analysis