EIF6 Antibody

$210.00$377.00

Cat. No.: 41365 Categories: ,

Description

Aliases

Eukaryotic translation initiation factor 6, B(2)GCN homolog, B4 integrin interactor, CAB, p27(BBP), EIF6

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P56537

Immunogen

Recombinant human Eukaryotic translation initiation factor 6 protein (1-245AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC;Not yet tested in other applications.

Background / Function

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

>95%,Protein G purified

Additional information

Size

50μg, 100μg

Certificate of Analysis