EML2 Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 41391 Categories: ,

Description

Aliases

EML2, EMAP2, EMAPL2

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O95834

Immunogen

Recombinant human Echinoderm microtubule-associated protein-like 2 protein (1-418AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”The consensus coding sequences of human breast and colorectal cancers.” Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list Velculescu V.E.Science 314:268-274(2006). [2]”Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ?-propeller domain.”Richards M.W., Law E.W., Rennalls L.P., Busacca S., O’Regan L., Fry A.M., Fennell D.A., Bayliss R.Proc. Natl. Acad. Sci. U.S.A. 111:5195-5200(2014). [3]”The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus.”Eichenmuller B., Everley P., Palange J., Lepley D., Suprenant K.A.J. Biol. Chem. 277:1301-1309(2002).

Additional information

Size

50μg, 100μg

Certificate of Analysis