Description
Aliases
EML2, EMAP2, EMAPL2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O95834
Immunogen
Recombinant human Echinoderm microtubule-associated protein-like 2 protein (1-418AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”The consensus coding sequences of human breast and colorectal cancers.” Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list Velculescu V.E.Science 314:268-274(2006). [2]”Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ?-propeller domain.”Richards M.W., Law E.W., Rennalls L.P., Busacca S., O’Regan L., Fry A.M., Fennell D.A., Bayliss R.Proc. Natl. Acad. Sci. U.S.A. 111:5195-5200(2014). [3]”The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus.”Eichenmuller B., Everley P., Palange J., Lepley D., Suprenant K.A.J. Biol. Chem. 277:1301-1309(2002).Additional information
| Size | 50μg, 100μg |
|---|
