ENSA Antibody

$210.00$377.00

Cat. No.: 43682 Categories: ,

Description

Aliases

ARPP-19e

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O43768

Immunogen

Recombinant human Alpha-endosulfine protein (1-121AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC;Recommended dilution:IHC:1:20-1:200

Background / Function

Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Alpha-endosulfine protein

Research

Cell Cycle

Additional information

Size

50μg, 100μg

Certificate of Analysis