Estrogen Receptor-a (Phospho-Tyr537) Antibody

$454.00

Cat. No.: 38891 Categories: ,

Description

Aliases

ER; ESR; ESR1; ESTR; NR3A1

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#: P03372;
NCBI Gene#: 2099;
N

Immunogen

Peptide sequence around phosphorylation site of tyrosine 537(P-L-Y(p)-D-L) derived from Human Estrogen Receptor-α.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Background / Function

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Sehime Temel, Endocrinology, Oct 2002; 143: 3974. Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302. Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 – R669. Marcello Maggiolini, Cancer Res., Oct 1999;

Conjugate

Unconjugated

Storage Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Tyr537

Additional information

Size

100?l

Certificate of Analysis