Description
Aliases
ER; ESR; ESR1; ESTR; NR3A1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P03372;
NCBI Gene#: 2099;
N
Immunogen
Peptide sequence around phosphorylation site of tyrosine 537(P-L-Y(p)-D-L) derived from Human Estrogen Receptor-α.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background / Function
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Sehime Temel, Endocrinology, Oct 2002; 143: 3974. Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302. Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 – R669. Marcello Maggiolini, Cancer Res., Oct 1999;
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Tyr537
Additional information
| Size | 100?l |
|---|
