Estrogen Receptor-a(Phospho-Ser104) Antibody

$454.00

Cat. No.: 38751 Categories: ,

Description

Aliases

ER; ESR; ESR1; ESTR; ESTRA

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P03372
NCBI Protein: NP_000116.2

Immunogen

Peptide sequence around phosphorylation site of serine 104 (S-V-S(p)-P-S) derived from Human Estrogen Receptor-a.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Predicted MW: 66kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444.Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857.Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.Kwon, Y. K. et al. (1997) J. Neurosci. 17, 8293-8299.Klapper, L. N. et al. (2000) Cancer Res. 60, 3384-3388.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser104

Additional information

Size

100?l

Certificate of Analysis