F3 Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 41539 Categories: ,

Description

Aliases

TF, Coagulation factor III, Thromboplastin, CD142, F3

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P13726

Immunogen

Recombinant human Tissue factor protein (33-251AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.” Zhang E., St Charles R., Tulinsky A. J. Mol. Biol. 285:2089-2104(1998). [2]”The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.” Banner D.W., D’Arcy A., Chene C., Winkler F.K., Guha A., Konigsberg W.H., Nemreson Y., Kirchhofer D. Nature 380:41-46(1995). [3]”The crystal structure of the extracellular domain of human tissue factor refined to 1.7-A resolution.” Muller Y.A., Ultsch M.H., de Vos A.M. J. Mol. Biol. 256:144-159(1995).

Additional information

Size

50μg, 100μg

Certificate of Analysis