Description
Aliases
TF, Coagulation factor III, Thromboplastin, CD142, F3
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P13726
Immunogen
Recombinant human Tissue factor protein (33-251AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.” Zhang E., St Charles R., Tulinsky A. J. Mol. Biol. 285:2089-2104(1998). [2]”The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.” Banner D.W., D’Arcy A., Chene C., Winkler F.K., Guha A., Konigsberg W.H., Nemreson Y., Kirchhofer D. Nature 380:41-46(1995). [3]”The crystal structure of the extracellular domain of human tissue factor refined to 1.7-A resolution.” Muller Y.A., Ultsch M.H., de Vos A.M. J. Mol. Biol. 256:144-159(1995).Additional information
Size | 50μg, 100μg |
---|