Fcmr Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

Regulator of Fas-induced apoptosis Toso, Faim3, Toso

Antibody Type

Polyclonal Antibody

Species

Mouse

Uniprot ID

A1KXC4

Immunogen

Recombinant mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)

Raised In

Rabbit

Species Reactivity

Mouse

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Fas apoptotic inhibitory molecule 3

Literature

[1]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Team Genome Res. 14:2121-2127(2004). [2]”The transcriptional landscape of the mammalian genome.” Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list Hayashizaki Y. Science 309:1559-1563(2005) . [3]Song Y., Jacob C.O. Submitted (JAN-2003).

Additional information

Size

50μg, 100μg

Certificate of Analysis