UDP-glucose–hexose-1-phosphate uridylyltransferase GALT
Recombinant human Galactose-1-phosphate uridylyltransferase protein (1-379AA)
ELISA;Not yet tested in other applications.
Background / Function
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature”Cloning and characterization of a cDNA encoding human galactose-1-phosphate uridyl transferase.” Reichardt J.K.V., Berg P.Mol. Biol. Med. 5:107-122(1988) ”Sequence of a cDNA encoding human galactose-1-phosphate uridyl transferas