GDF9 Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

GDF-9, GDF9

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O60383

Immunogen

Recombinant human Growth/differentiation factor 9 protein (320-454AA)

Raised In

Rabbit

Species Reactivity

human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Cardiovascular

Literature

[1]”Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure.” Wang B., Wen Q., Ni F., Zhou S., Wang J., Cao Y., Ma X.Clin. Endocrinol. (Oxf.) 72:135

Additional information

Size

50μg, 100μg

Certificate of Analysis