Description
Aliases
GINS complex subunit 2, CGI-122, DC5, HSPC037, PSF2, GINS2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9Y248
Immunogen
Recombinant human DNA replication complex GINS protein PSF2 protein (1-185AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
DNA replication complex GINS protein PSF2
Literature
[1]”Novel genes expressed in human dendritic cells.” Li Y., Peng Y., Li N., Gu W., Han Z., Fu G., Chen Z. Submitted (NOV-1999). [2]”Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S. Nat. Genet. 36:40-45(2004). [3]”ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.” Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. Science 316:1160-1166(2007).Additional information
| Size | 50μg, 100μg, 50μl, 100μl |
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