Description
General Description
Glutathione Reduced (GSH) is a thiol compound, associated with catabolism and transportation. Plasma GSH levels are associated with Parkinson′s diseases, Alzheimer′s, diabetes, macular degeneration, and HIV (human immunodeficiency virus) disease. May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose. L-Glutathione reduced is used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads and also used to prepare a standard curve for GSH analyses.
Glutathione Reduced (GSH) is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
CAS Number: 70-18-8
Synonyms: L-Glutathione Reduced, GSH, Gamma-Glutamylcysteinylglycine; 2-amino-4-({1-[(carboxymethyl) carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.321 g/mol
InChI Key: RWSXRVCMGQZWBV-UHFFFAOYSA-N
STORAGE: Store at 4°C, Protected from light.
Additional information
| Size | 1 g, 5 g, 10 g, 25 g, 50 g, 100 g, 250 g, 500 g, 1 Kg |
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