GOSR2 Antibody

$210.00$377.00

Cat. No.: 42045 Categories: ,

Description

Aliases

27 kDa Golgi SNARE protein, Membrin, GS27, GOSR2

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O14653

Immunogen

Recombinant human Golgi SNAP receptor complex member 2 protein (1-190AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200

Background / Function

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Golgi SNAP receptor complex member 2

Literature

[1]”A mutation in the Golgi Qb-SNARE gene GOSR2 causes progressive myoclonus epilepsy with early ataxia.” Corbett M.A., Schwake M., Bahlo M., Dibbens L.M., Lin M., Gandolfo L.C., Vears D.F., O’Sullivan J.D., Robertson T., Bayly M.A., Gardner A.E., Vlaar A.M., Korenke G.C., Bloem B.R., de Coo I.F., Verhagen J.M., Lehesjoki A.E., Gecz J., Berkovic S.F. Am. J. Hum. Genet. 88:657-663(2010). [2]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Team Genome Res. 14:2121-2127(2003). [3]”DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.” Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. Nusbaum C. Nature 440:1045-1049(2005).

Additional information

Size

50μg, 100μg

Certificate of Analysis