Description
Aliases
General transcription factor IIH polypeptide 5 TFB5 ortholog TFIIH basal transcription factor complex TTD-A subunit GTF2H5 C6orf175, TTDA
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q6ZYL4
Immunogen
Recombinant human General transcription factor IIH subunit 5 protein (1-71AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Epigenetics and Nuclear Signaling
Literature
[1]”A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A and stabilizes TFIIH.”Giglia-Mari G., Coin F., Ranish J.A., Hoogstraten D., Theil A., Wijgers N., Jaspers N.G.J., Raams A., Argentini M.,Additional information
Size | 50μg, 100μg |
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