H2AFB1 Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

Histone H2A-Bbd type 1, H2A Barr body-deficient, H2A.Bbd, H2AFB1

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P0C5Y9

Immunogen

Recombinant human Histone H2A-Bbd type 1 protein (1-115AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

>95%,Protein G purified

Additional information

Size

50μg, 100μg

Certificate of Analysis