HAVCR2 Antibody, Biotin conjugated

Description

Aliases

T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3, TIM-3, HAVCR2, TIM3, TIMD3

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q8TDQ0

Immunogen

Recombinant human Hepatitis A virus cellular receptor 2 protein (22-202AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Immunology

Literature

[1] “Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.”Monney L., Sabatos C.A., Gaglia J.L., Ryu A., Waldner H., Chernova T., Manning S., Greenfield E.A., Coyle A.J., Sobel R.A., Freeman G.J., K

Additional information

Size	50μg, 100μg