HBB Antibody

$210.00$377.00

Cat. No.: 42245 Categories: ,

Description

Aliases

Beta-globin, Hemoglobin beta chain, HBB

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P68871

Immunogen

Recombinant human Hemoglobin subunit beta protein (1-147AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC;Recommended dilution:IHC:1:20-1:200

Background / Function

Involved in oxygen transport from the lung to the various peripheral tissues. LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure. Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Hemoglobin subunit beta

Literature

[1]”The differently expressed genes in the lymphocyte of recovered SARS patients.” Fan B., Xie L., Guan X. Submitted (NOV-2003). [2]”Thalassaemic trait cause by C-T substitution at position -90 in proximal CACCC box of beta-globin gene in China family.” Li W.J. Submitted (FEB-2003). [3]”A new hemoglobin, beta chain variant ‘Hb S-Wake’ confirmed to be on the same chromosome with hemoglobin S mutation, detected in an African-American family.” Kutlar F., Lallinger R.R., Holley L., Glendenning M., Kutlar A. Submitted (JUN-2002).

Additional information

Size

50μg, 100μg

Certificate of Analysis