HIST1H2AG Antibody

$210.00$377.00

Cat. No.: 42289 Categories: ,

Description

Aliases

Histone H2A type 1, H2A.1, HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P0C0S8

Immunogen

Recombinant human Histone H2A type 1 protein (2-130AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, ChIP

Background / Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”The human and mouse replication-dependent histone genes.”Marzluff W.F., Gongidi P., Woods K.R., Jin J., Maltais L.J.Genomics 80:487-498(2002). [2]”The DNA sequence and analysis of human chromosome 6.” Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. Beck S. Nature 425:805-811(2003).

Additional information

Size

50μg, 100μg

Certificate of Analysis