HIST1H2BC Antibody, HRP conjugated

$210.00$377.00

Description

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P62807

Immunogen

Recombinant human Histone H2B type 1-C/E/F/G/I protein (2-125AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Histone H2B type 1-C/E/F/G/I protein

Research

Epigenetics and Nuclear Signaling

Literature

[1]”Isolation and characterization of two human H1 histone genes within clusters of core histone genes.”Albig W., Kardalinou E., Drabent B., Zimmer A., Doenecke D.Genomics 10:940-948(1991) [2]”Human histone gene organization: nonregular arrangement withi

Additional information

Size

50μg, 100μg

Certificate of Analysis