Hist1h2bm Antibody

$220.50$395.85

Cat. No.: 42301 Categories: ,

Description

Aliases

H2B 291B, Hist1h2bm

Antibody Type

Polyclonal Antibody

Species

Mouse

Uniprot ID

P10854

Immunogen

Recombinant mouse Histone H2B type 1-M protein (2-126AA)

Raised In

Rabbit

Species Reactivity

Mouse

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Others

Literature

[1] “Mouse histone H2A and H2B genes: four functional genes and a pseudogene undergoing gene conversion with a closely linked functional gene.”Liu T.-J., Liu L., Marzluff W.F.Nucleic Acids Res. 15:3023-3039(1987) [2] “The human and mouse replication-de

Additional information

Size

50μg, 100μg

Certificate of Analysis