Description
Aliases
H2B 291B, Hist1h2bm
Antibody Type
Polyclonal Antibody
Species
Mouse
Uniprot ID
P10854
Immunogen
Recombinant mouse Histone H2B type 1-M protein (2-126AA)
Raised In
Rabbit
Species Reactivity
Mouse
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Others
Literature
[1] “Mouse histone H2A and H2B genes: four functional genes and a pseudogene undergoing gene conversion with a closely linked functional gene.”Liu T.-J., Liu L., Marzluff W.F.Nucleic Acids Res. 15:3023-3039(1987) [2] “The human and mouse replication-deAdditional information
Size | 50μg, 100μg |
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