H3 histone antibody; HIST1H3A antibody; Histone cluster 1; H3a antibody
A synthetic Di-methylated peptide corresponding to residues surrounding Lys4 of human histone H3.
Human Rat Mouse
WB Recommended dilution: Western blotting: 1:1000~1:2000,
Background / Function
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Purified Rabbit IgG, 1mg/ml in PBS pH7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antigen Affinity Purified