H3t; H3.4; H3/g; H3FT;
Gene ID: 8290 Swiss Prot: Q16695
A synthetic peptide of human H3K14me2
Human Mouse Rat
WB IHC IF Recommended dilution: WB 1:500 – 1:2000
IF 1:20- 1:50
Background / Function
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antigen Affinity Purified