Histone H3K14me2 Polyclonal Antibody

$511.35

Cat. No.: 39120 Categories: ,

Description

Aliases

H3t; H3.4; H3/g; H3FT;

Antibody Type

Polyclonal Antibody

Uniprot ID

Gene ID: 8290 Swiss Prot: Q16695

Immunogen

A synthetic peptide of human H3K14me2

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC IF Recommended dilution: WB 1:500 – 1:2000

IHC 1:50- 1:200

IF 1:20- 1:50

Background / Function

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Conjugate

Unconjugated

Storage Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antigen Affinity Purified

Modification

K14me2

Additional information

Size

100?l

Certificate of Analysis