Histone H3(Phospho-Ser28) Rabbit Polyclonal Antibody

$454.00

Cat. No.: 38664 Categories: ,

Description

Aliases

H3 histone antibody; HIST1H3A antibody; Histone cluster 1; H3a antibody

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#:P68431

Immunogen

Peptide sequence around phosphorylation site of serine 28(R-K-S(p)-A-P) derived from Human Histone H3.

Raised In

Rabbit

Species Reactivity

Human Rat Mouse

Tested Applications

WB Recommended dilution: Western blotting: 1:200~1:500,

Background / Function

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Conjugate

Unconjugated

Storage Buffer

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser28

Additional information

Size

100?l

Certificate of Analysis