HMGB1 Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 43569 Categories: ,

Description

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P09429

Immunogen

Recombinant human High mobility group protein B1 protein (8-179AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

High mobility group protein B1 protein

Research

Epigenetics and Nuclear Signaling

Literature

[1] “A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1.”Wen L., Huang J.K., Johnson B.H., Reeck G.R.Nucleic Acids Res. 17:1197-1214(1989) [2] “The active gene that encodes human high mobility group 1 protein (HMG1) contains

Additional information

Size

50μg, 100μg

Certificate of Analysis