HMGCR Antibody

Aliases HMGCR Antibody Type Polyclonal Antibody Species Human Uniprot ID P04035 Immunogen Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA) Raised In Rabbit Species Reactivity Human Tested Applications ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200, IF:1:50-1:200 Background / Function Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins. Isotype IgG Conjugate Unconjugated Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Caprylic Acid Ammonium Sulfate Precipitation purified Research Metabolism Literature [1] “Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.” Luskey K.L., Stevens B.J. Biol. Chem. 260:10271-10277(1985) [2] “Human HMG-CoA reducta