Cepham Life Sciences Hybridization Buffer, DNA & RNA is a formamide-based solution for use in the pre-hybridization and hybridization of biotinylated nucleic acid probes to nucleic acids fixed on membranes.
As a pre-hybridization solution, the buffer blocks sites on the membrane and prevents nonspecific binding of biotinylated probe.
As a hybridization solution, the buffer facilitates binding of biotinylated probes to homologous RNA or DNA on a membrane.
PRODUCT CITATIONS:
- Mashaghi, Alireza et al (2024) Correlating Protein Aggregate Structure with Cellular Function in Differentiated Muscle Cells: Discriminating Pathogenic from Non-Pathogenic Forms. bioRxiv https://doi.org/10.1186/s12934-022-01899-x