Description
Aliases
IBP-1, IGF-binding protein 1, IGFBP-1, Igfbp-1, Igfbp1
Antibody Type
Polyclonal Antibody
Species
Mouse
Uniprot ID
P47876
Immunogen
Recombinant mouse Insulin-like growth factor-binding protein 1 protein (26-272AA)
Raised In
Rabbit
Species Reactivity
Mouse
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Insulin-like growth factor-binding protein 1
Literature
[1]”Structure and localization of the IGFBP-1 gene and its expression during liver regeneration.” Lee J., Greenbaum L., Haber B.A., Nagle D., Lee V., Miles V., Mohn K.L., Bucan M., Taub R. Hepatology 19:656-665(1994). [2]”Lineage-specific biology revealed by a finished genome assembly of the mouse.” Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009). [3]”cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins.” Schuller A.G.P., Groffen C., van Neck J.W., Zwarthoff E.C., Drop S.L.S. Mol. Cell. Endocrinol. 104:57-66(1994).Additional information
Size | 50μg, 100μg |
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