JAK1(Phospho-Tyr1022) Antibody

$454.00

Cat. No.: 38780 Categories: ,

Description

Aliases

Janus kinase 1

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P23458
NCBI Protein: NP_002218.2

Immunogen

Peptide sequence around phosphorylation site of tyrosine 1022 (K-E-Y(p)-Y-T) derived from Human JAK1.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC Recommended dilution: Predicted MW: 130kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.Zheng H, et al.(2005)Mol Cell Proteomics. 4(6):721-730.Wang R, et al.(2003) Arch Biochem Biophys. 410(1): 7-15.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Tyr1022

Additional information

Size

100?l

Certificate of Analysis