MEF2C (Phospho-Ser396) Antibody

$454.00

Cat. No.: 38930 Categories: ,

Description

Aliases

Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C; Similar to MADS box transcription enhancer factor 2 polypeptide C;

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#: Q06413;
NCBI Gene#: 4208;
N

Immunogen

Peptide sequence around phosphorylation site of Serine 396(P-V-S(p)-P-P) derived from Human MEF2C.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Background / Function

MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described. Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550(1993).McDermott J.C., Mol. Cell. Biol. 13:2564-2577(1993).Wang A.H., Mol. Cell. Biol. 19:7816-7827(1999).

Conjugate

Unconjugated

Storage Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser396

Additional information

Size

100?l

Certificate of Analysis