Myc(Phospho-Ser373) Antibody

$454.00

Cat. No.: 38736 Categories: ,

Description

Aliases

c-myc

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P01106
NCBI Protein: NP_002458.2

Immunogen

Peptide sequence around phosphorylation site of serine 373 derived from Human Myc.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC Recommended dilution: Predicted MW: 60kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5′-CAC[GA]TG-3′. Seems to activate the transcription of growth-related genes.Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.Blackwood E M, et al. (1991) Science. 251:1211-1217.Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser373

Additional information

Size

100μl

Certificate of Analysis