NMDAR2B(phospho-Tyr1474) Antibody

$454.00

Cat. No.: 38787 Categories: ,

Description

Aliases

GRIN2B; NMDE2; NME2; NR2B; NR3

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: Q13224
NCBI Protein: NP_000825.2

Immunogen

Peptide sequence around phosphorylation site of Tyr1474 (H-V-Y(p)-E-K) derived from Human NMDAR2B.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IF Recommended dilution: Predicted MW: 190kdWestern Blot: 1:500~1000, Immunofluorescence: 1:100~1:200

Background / Function

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Babb TL et al.Epilepsy Res. 2005 Mar-Apr;64(1-2):23-30 Chazot PL. Curr Med Chem. 2004 Feb;11(3):389-96 Kakegawa W, et al.Eur J Neurosci. 2003 Feb;17(4):887-91

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Tyr1474

Additional information

Size

100?l

Certificate of Analysis