NPHS1 Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 43548 Categories: ,

Description

Aliases

Renal glomerulus-specific cell adhesion receptor, NPHN, NPHS1

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O60500

Immunogen

Recombinant human Nephrin protein (23-257AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]Interaction with podocin facilitates nephrin signaling. Huber T.B., Kottgen M., Schilling B., Walz G., Benzing T. J. Biol. Chem. 276:41543-41546(2001). [2]Phosphoproteome of resting human platelets. Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J., Schuetz C., Walter U., Gambaryan S., Sickmann A. J. Proteome Res. 7:526-534(2008). [3]A familial childhood-onset relapsing nephrotic syndrome. Kitamura A., Tsukaguchi H., Hiramoto R., Shono A., Doi T., Kagami S., Iijima K. Kidney Int. 71:946-951(2007).

Additional information

Size

50μg, 100μg

Certificate of Analysis