N-glycosylase/DNA lyaseIncluding the following 2 domains:8-oxoguanine DNA glycosylase (EC:3.2.2.-)DNA-(apurinic or apyrimidinic site) lyase (EC:22.214.171.124), AP lyase, OGG1, MMH, MUTM, OGH1
Recombinant human N-glycosylase/DNA lyase protein (1-345AA)
ELISA;Not yet tested in other applications.
Background / Function
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3′ to the lesion.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified