ORC4 Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 43693 Categories: ,

Description

Aliases

ORC4, ORC4L

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O43929

Immunogen

Recombinant human Origin recognition complex subunit 4 protein (1-436AA)

Raised In

Rabbit

Species Reactivity

human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Transcription

Literature

[1]”Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome.”Guernsey D.L., Matsuoka M., Jiang H., Evans S., Macgillivray C., Nightingale M., Perry S., Ferguson M., LeBlanc M., Paquette J., Patry L., Rideout A.L., Thomas

Additional information

Size

50μg, 100μg

Certificate of Analysis