OSR1 (Phospho-Thr185) Antibody

$454.00

Cat. No.: 38915 Categories: ,

Description

Aliases

OXSR1; kinase OSR1; Oxidative-stress responsive 1;

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#: O95747;
NCBI Gene#: 9943;
N

Immunogen

Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Background / Function

Oxidative-stress responsive 1 gene is located in the vicinity of three others genes – GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stressTamari M., J. Hum. Genet. 44:116-120(1999).Kikuno R., DNA Res. 6-197-205(1999).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Conjugate

Unconjugated

Storage Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Thr185

Additional information

Size

100μl

Certificate of Analysis