Description
Aliases
KS6A1; MAPKAP-K1a; RPS6KA1; RSK1; S6K-alpha 1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q15418
NCBI Protein: NP_001006666.
Immunogen
Peptide sequence around phosphorylation site of threonine 348 (S-R-T(p)-P-R) derived from Human p90RSK.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC IF Recommended dilution: Predicted MW: 90kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background / Function
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.Silverman E, et al. Mol Cell Biol. 2004 Dec; 24(24): 10573-10583.Andrew D, et al. Biochem J. 2006 February 1; 393(Pt 3): 715
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Thr348
Additional information
| Size | 100?l |
|---|
