Aromatic esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
Recombinant Human Serum paraoxonase/arylesterase 1 protein (2-355AA)
ELISA;Not yet tested in other applications.
Background / Function
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified
LiteratureCharacterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence.Hassett C., Richter R.J., Humbert R., Chapline C., Crabb J.W., Omiecinski C.J., Furlong C.E.Biochemistry 30:10141-10149(1991)