Description
Aliases
P105-RB; PP105; PP110; RB1;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P06400;
NCBI Gene#: 5925;
N
Immunogen
Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background / Function
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression (‘cure’) occurs in some cases.Lee W.-H., Nature 329:642-645(1987).Lee W.-H., Science 235:1394-1399(1987).Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Ser608
Additional information
| Size | 100?l |
|---|
