Retinoblastoma (Phospho-Ser608) Antibody

$454.00

Cat. No.: 38908 Categories: ,

Description

Aliases

P105-RB; PP105; PP110; RB1;

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#: P06400;
NCBI Gene#: 5925;
N

Immunogen

Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma.

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB IHC Recommended dilution: Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Background / Function

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression (‘cure’) occurs in some cases.Lee W.-H., Nature 329:642-645(1987).Lee W.-H., Science 235:1394-1399(1987).Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).

Conjugate

Unconjugated

Storage Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser608

Additional information

Size

100?l

Certificate of Analysis