37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin-binding protein, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, RPSA, LAMBR, LAMR1
Recombinant human 40S ribosomal protein SA protein (2-294AA)
ELISA;Not yet tested in other applications.
Background / Function
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature”Crystal structure of the human laminin receptor precursor.”Jamieson K.V., Wu J., Hubbard S.R., Meruelo D.J. Biol. Chem. 283:3002-3005(2008). ”Initial characterization of the human central proteome.”Burkard T.R., Planyavsky