Description
Aliases
S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100A1, S100A
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P23297
Immunogen
Recombinant human Protein S100-A1 protein (2-94AA)
Raised In
Rabbit
Species Reactivity
human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Signal Transduction
Literature
[1]”Post-translational S-nitrosylation is an endogenous factor fine tuning the properties of human S100A1 protein.”Lenarcic Zivkovic M., Zareba-Koziol M., Zhukova L., Poznanski J., Zhukov I., Wyslouch-Cieszynska A.J. Biol. Chem. 287:40457-40470(2012).Additional information
| Size | 50μg, 100μg |
|---|
